4-D Photoacoustic Tomography

Prospects of photoacoustic tomography.

Commercially available high-resolution three-dimensional optical imaging modalities-including confocal microscopy, two-photon microscopy, and optical coherence tomography-have fundamentally impacted biomedicine. Unfortunately, such tools cannot penetrate biological tissue deeper than the optical transport mean free path (approximately 1 mm in the skin). Photoacoustic tomography, which combines ...

Compressed-sensing photoacoustic computed tomography in vivo with partially known support

Compressed sensing (CS) can recover sparse signals from undersampled measurements. In this work, we have developed an advanced CS framework for photoacoustic computed tomography (PACT). During the reconstruction, a small part of the nonzero signals’ locations in the transformed sparse domain is used as partially known support (PKS). PACT reconstructions have been performed with under-sampled in...

Limited-view photoacoustic tomography utilizing backscatterers as virtual transducers

Photoacoustic Tomography of Human Hepatic Malignancies Using Intraoperative Indocyanine Green Fluorescence Imaging

Recently, fluorescence imaging following the preoperative intravenous injection of indocyanine green has been used in clinical settings to identify hepatic malignancies during surgery. The aim of this study was to evaluate the ability of photoacoustic tomography using indocyanine green as a contrast agent to produce representative fluorescence images of hepatic tumors by visualizing the spatial...

Modeling Photoacoustic Tomography using k-Wave

Photoacoustic tomography (PAT) is a hybrid imaging technique that offers similar medical potential as ultrasound and optical imaging. Although efforts to innovate Photoacoustic scanners have been scarce, newer developments such as k-Wave will enable their optimal imaging capability. Despite k-Wave’s ability to simulate PAT, few researchers utilize this technology. Thus, this project explored th...

XWH - 09 - 1 - 0299 TITLE : Photoacoustic Imaging of Epilepsy PRINCIPAL

Photoacoustic tomography (PAT) is an emerging non-invasiveimaging technique with great potential for a wide range of biomedicalimaging applications. However, the conventional PAT reconstructionalgorithms often provide distorted images with strong artifacts in caseswhen the signals are collected from few measurements or over an aperturethat does not enclose the object. In thi...